Prebiotic Evolution: ATP Energy

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ATP Synthesis with a Single Enzyme

If a single enzyme ever created ATP directly from an oxidation reaction, then it did not survive evolution. So instead consider the dehydrogenase that is involved in glycolysis (the process life use to metabolize sugar), Glyceralehyde 3-P dehydrogenase or G3PD for short. G3PD facilitates an oxidation reaction, and uses the energy released to create a high energy phosphate bond. This high energy phosphate is subsequently transferred to ATP by another enzyme. In theory, an enzyme with a molecular knowledge on par with G3PD should be able to create ATP from ADP. So this section will calculate the knowledge in G3PD, and use it as a benchmark to model a hypothetical enzyme that may have existed on the primitive earth.
         

next: The Evolution of 3PD Knowledge

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Navigation Menu Chapter 14


Chapter 14: Information Required for ATP Synthesis

       Oxidation Releases Energy
       ATP Created By Proton Gradients
       ATP Synthesis with a Single Enzyme
       G3PD Knowledge
       Molecular Knowledge in G3PD
        Correction for Primordial Soup
        Odds of ATP and Adenine Evolution
       Does this Approach Generate False Knowledge
       ATP Synthase

PDF: ATP Synthesis (2 Mb)

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